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Accelerating the cure for Long COVID

Over 100 million people worldwide suffer from Long COVID, without approved treatments or diagnostics. Patients can’t afford to wait.

Treatment Leaderboard

#
Treatment
Stage
Category
Community Rating
1
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
9
2
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
8
3
Ensitrelvir
Pre-clinical
Long-course antiviral
6
4
Pemgarda
Pre-clinical
Monoclonal antibody
6
5
Metformin
Pre-clinical
Long-course antiviral
5
6
PEG Interferon Lambda
Pre-clinical
Immune modulator
5
7
IVIG
Pre-clinical
Monoclonal antibody
5
8
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
5
9
Paxlovid 
Pilot
Long-course antiviral
4
10
Remdesivir
Study design
Long-course antiviral
3
11
Molnupiravir
Pre-clinical
Long-course antiviral
2
1
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
9
2
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
8
3
Ensitrelvir
Pre-clinical
Long-course antiviral
6
4
Pemgarda
Pre-clinical
Long COVID Cures
6
5
Metformin
Pre-clinical
Long-course antiviral
5
6
PEG Interferon Lambda
Pre-clinical
Immune modulator
5
7
IVIG
Pre-clinical
Monoclonal antibody
5
8
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
5
9
Paxlovid 
Pilot
Long-course antiviral
4
10
Remdesivir
Study design
Long-course antiviral
3
11
Molnupiravir
Pre-clinical
Long-course antiviral
2
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
Rank
1
Community Rating
9
Learn More
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
Rank
2
Community Rating
8
Learn More
Ensitrelvir
Pre-clinical
Long-course antiviral
Rank
3
Community Rating
6
Learn More
Pemgarda
Pre-clinical
Long COVID Cures
Rank
4
Community Rating
6
Learn More
Metformin
Pre-clinical
Long-course antiviral
Rank
5
Community Rating
5
Learn More
PEG Interferon Lambda
Pre-clinical
Immune modulator
Rank
6
Community Rating
5
Learn More
IVIG
Pre-clinical
Monoclonal antibody
Rank
7
Community Rating
5
Learn More
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
Rank
8
Community Rating
5
Learn More
Paxlovid 
Pilot
Long-course antiviral
Rank
9
Community Rating
4
Learn More
Remdesivir
Study design
Long-course antiviral
Rank
10
Community Rating
3
Learn More
Molnupiravir
Pre-clinical
Long-course antiviral
Rank
11
Community Rating
2
Learn More
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
Rank
1
Community Rating
9
Learn More
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
Rank
2
Community Rating
8
Learn More
Ensitrelvir
Pre-clinical
Long-course antiviral
Rank
3
Community Rating
6
Learn More
Pemgarda
Pre-clinical
Monoclonal antibody
Rank
4
Community Rating
6
Learn More
Metformin
Pre-clinical
Long-course antiviral
Rank
5
Community Rating
5
Learn More
PEG Interferon Lambda
Pre-clinical
Immune modulator
Rank
6
Community Rating
5
Learn More
IVIG
Pre-clinical
Monoclonal antibody
Rank
7
Community Rating
5
Learn More
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
Rank
8
Community Rating
5
Learn More
Paxlovid 
Pilot
Long-course antiviral
Rank
9
Community Rating
4
Learn More
Remdesivir
Study design
Long-course antiviral
Rank
10
Community Rating
3
Learn More
Molnupiravir
Pre-clinical
Long-course antiviral
Rank
11
Community Rating
2
Learn More

Have your say

Have a hunch one of these might work, or (even better) tried it yourself? Vote here and add your voice to the conversation.

Unlocking Real-World Evidence

Centralized data from individual patient and clinician experiences, creating the infrastructure layer that publicly amplifies the private experiments already happening.

Surfacing Signal from Noise

Patient data and experimentation are structured to rapidly reveal which treatments deliver outcomes—and for whom—turning fragmented insights into clear, actionable discoveries.

Accelerating Discoveries into Scalable Treatments

We reward patients for high-quality contributions — from validated symptom surveys to biomarker data — through milestone prizes and direct compensation. This approach ensures robust, actionable data and speeds the path to scalable treatments beyond what traditional systems can achieve.

Transparent and Decentralized

Powered by decentralized science, patients and researchers hold governance tokens granting them a voice in research priorities and ethical IP use.

Are you working on a breakthrough treatment for Long COVID?

There are a few theories about what causes Long COVID. We’re focused on one - viral persistence, or virus that sticks around after the initial infection. If you have ideas for antiviral or immune modulatory approaches to clearing persistent virus, submit them here and we may fund them.

Submit a treatment

Join the mission to accelerate a cure.

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